Immunotherapy

CANCER IMMUNOTHERAPY AKA IMMUNO-ONCOLOGY

A form of cancer treatment that uses/harnesses the body’s own immune system to stop cancer.

It comes in a variety of forms and can be used in combination with surgery, chemotherapy, and radiation or targeted therapies:

• Antibodies
• B Cells
• CD8 + Killer T Cells
• Cytokines
• Exosomes

• Dendritic Cells
• CD4 + Helper T Cells
• Regulatory T Cells
• Macrophages

Tumours exploit T-cell checkpoints designed to prevent autoimmunity. Inhibitors of these T-cell ‘brakes’ can result in cancer clearance

T-cells can be expanded from patient tumour to large number and reinfused back into patient blood leading to cancer clearance.

CAR-T : Patient T-cells can be engineered with cancer-specific chimeric (CARs) antigen T-cell receptors and transfused back into patient blood

TCR-T : Patient T-cells can also be equipped with T-cell receptors (TCRs) from cancer survivor’s blood

Knowledge of what works will allow broad spectrum therapeutic cancer vaccination.

Therapies that inhibit vascular endothelial growth factor (VEGF) signaling, have improved the outlook for patients with some cancers.

• Targets cancer cells specifically and does not affect healthy cells

• Immune System ‘memory’ will target cancer if it returns

• Can ‘adapt’ if cancer mutates and destroy the ‘new’ cancer

• Immuno-oncology therapies are being approved globally and having very successful outcomes in some cancers

Immunotherapy is helping extend and save lives of patients right now!

• Targets cancer cells specifically and does not affect healthy cells

• Immune System ‘memory’ will target cancer if it returns

• Can ‘adapt’ if cancer mutates and destroy the ‘new’ cancer

• Immuno-oncology therapies are being approved globally and having very successful outcomes in some cancers

Immunotherapy is helping extend and save lives of patients right now!